Genetic control of disease in an experimental model for Sjögren's syndrome
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Genetic control of disease in an experimental model for Sjögren's syndrome. / Andersson, Åsa Inga Maria.
In: Arthritis Research & Therapy, Vol. 11, No. 1, 2009, p. 102.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Genetic control of disease in an experimental model for Sjögren's syndrome
AU - Andersson, Åsa Inga Maria
N1 - Keywords: Animals; Chromosome Mapping; Disease Models, Animal; Genetic Predisposition to Disease; Mice; Mice, Inbred NOD; Sjogren's Syndrome
PY - 2009
Y1 - 2009
N2 - Sjögren's syndrome is an autoimmune disease with a complex etiology depending on hereditary and environmental factors. The disease is characterized by lymphocytic infiltration and inflammation in the salivary and lacrimal glands, leading to oral and ocular dryness. To understand the genetic susceptibility in Sjögren's syndrome, studies of disease phenotypes have been performed in the non-obese diabetic (NOD) mouse. By the identification of genetic regions controlling development of autoimmune exocrinopathy in the NOD mouse and by reducing one of these regions considerably, Nguyen et al. in a recent issue of Arthritis Research and Therapy propose candidate genes for development of Sjögren's syndrome.
AB - Sjögren's syndrome is an autoimmune disease with a complex etiology depending on hereditary and environmental factors. The disease is characterized by lymphocytic infiltration and inflammation in the salivary and lacrimal glands, leading to oral and ocular dryness. To understand the genetic susceptibility in Sjögren's syndrome, studies of disease phenotypes have been performed in the non-obese diabetic (NOD) mouse. By the identification of genetic regions controlling development of autoimmune exocrinopathy in the NOD mouse and by reducing one of these regions considerably, Nguyen et al. in a recent issue of Arthritis Research and Therapy propose candidate genes for development of Sjögren's syndrome.
KW - Former Faculty of Pharmaceutical Sciences
U2 - 10.1186/ar2583
DO - 10.1186/ar2583
M3 - Journal article
C2 - 19216731
VL - 11
SP - 102
JO - Arthritis Research & Therapy
JF - Arthritis Research & Therapy
SN - 1478-6354
IS - 1
ER -
ID: 16862563