Oxygen Constraints on Microbial Secretomes during Plant Cell Wall Turnover
The OxyMiST consortium will establish how oxygen contributes to whole plant cell wall (PCW) degradation by microbial secretomes. The role of oxygen in promoting and restricting these enzymatic processes has been largely overlooked in the past.
The project extends from environmental microbial diversity to metasecretomics, from controlled laboratory PCW degradation to defined enzyme reactivity, and from molecular structure to fine-tuned enzymatic modifications. Leading scientists in Copenhagen, Marseille and Cambridge will take advantage of existing expertise and infrastructure to develop new advanced methodologies such as phylopeptidomics for this study.
The primary outcome of this research will be a completely revised view of the dynamic and temporal changes in the spectrum and activity of enzymes secreted during the turnover of PCWs. In particular, the constraint imparted by the dissolved O2 in two ecosystems (peat and wood) will be defined.
The project will integrate research carried out at the three research institutions:
- French National Institute for Agricultural Research, Food and Environment – INRAE, Marseille
- The University of Cambridge - UC, Cambridge
- The University of Copenhagen - UCPH, Copenhagen.
The work is organised in three broad themes encompassing ecology, microbiology and enzymology.
You can present the most important publications here. Include a link to full publication list if possible.
Professor Francis Martin
INRAE, Nancy, France
Senior Science Manager Kristian B. Krogh
Professor Henrik Scheller
Berkley University of California
+ 2 NN
|Helle Jakobe Martens||Associate Professor||+4528960218|
|Johan Ørskov Ipsen||Postdoc||+4535336185|
|Jonas Thomsen||PhD Fellow|
|Karsten Wiberg Andersen||PhD Fellow||+4535331784|
|Katja Salomon Johansen||Professor||+4535333706|
|Signe Lett||Assistant Professor||+4535326162|
|Søren Brander||Assistant Professor||+4535331261|
|Søren Michael Nielsen||Laboratory Technician||+4535336197|
|Tania Fredborg Nielsen||Academic Research Officer||+4535331280|
External members University of Cambridge:
|Paul Dupree||PI, Professor|
|Darragh Kelleher||PhD student|
|Xioalan Yu||Technical Scientist|
External members INRAE:
|Jean-Guy Berrin||PI, Senior research scientist|
|Marie-Noelle Rosso||Research scientist|
|Lionel Tarrago||Research scientist|
|Nicolas Terrapon||Assistant Professor|
Meet us on
The OxyMiST project is funded by a six year grant from the Novo Nordisk Foundation, Grant number NNF20OC0059697
Project: Oxygen Constraints on Microbial Secretomes during Plant Cell Wall Turnover (OxyMiST)
Period: Apr. 2021 – Mar. 2027