Population-level impact, herd immunity, and elimination after human papillomavirus vaccination: a systematic review and meta-analysis of predictions from transmission-dynamic models

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  • Marc Brisson
  • Élodie Bénard
  • Mélanie Drolet
  • Johannes A Bogaards
  • Iacopo Baussano
  • Simopekka Vänskä
  • Mark Jit
  • Marie-Claude Boily
  • Megan A Smith
  • Johannes Berkhof
  • Karen Canfell
  • Harrell W Chesson
  • Emily A Burger
  • Yoon H Choi
  • Birgitte Freiesleben De Blasio
  • Sake J De Vlas
  • Giorgio Guzzetta
  • Jan A C Hontelez
  • Johannes Horn
  • Jane J Kim
  • Fulvio Lazzarato
  • Suzette M Matthijsse
  • Rafael Mikolajczyk
  • Andrew Pavelyev
  • Matthew Pillsbury
  • Leigh Anne Shafer
  • Stephen P Tully
  • Hugo C Turner
  • Cara Usher
  • Cathal Walsh
BackgroundModelling studies have been widely used to inform human papillomavirus (HPV) vaccination policy decisions; however, many models exist and it is not known whether they produce consistent predictions of population-level effectiveness and herd effects. We did a systematic review and meta-analysis of model predictions of the long-term population-level effectiveness of vaccination against HPV 16, 18, 6, and 11 infection in women and men, to examine the variability in predicted herd effects, incremental benefit of vaccinating boys, and potential for HPV-vaccine-type elimination.
Original languageEnglish
JournalThe Lancet Public Health
Volume1
Issue number1
Pages (from-to)e8-e17
Number of pages10
ISSN2468-2667
DOIs
Publication statusPublished - 2016

Bibliographical note

doi: 10.1016/S2468-2667(16)30001-9

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