Biopolymers and redox enzymes
The aim is to both understand the molecular mechanisms and the systems in which the enzymes work. Our laboratories are equipped with specialised instruments that allow for study the role of oxygen in the degradation processes.
Special attention is given to enzymes called lytic polysaccharide monooxygenases (LPMOs). These enzyme are mononuclear copper enzymes that use oxygen-species for catalysis.
LPMOs are likely to have several functions in biology and are important for saprotrophic fungal lifestyle. Importantly, they initiate degradation of cellulose by cleaving glycosidic bonds at places that are not accessible cellulose hydrolases.
NNF Synergy grant "Mechanisms of lytic polysaccharide monooxygenases in fungal pathogenesis: directing polysaccharide structure and metabolism in Cryptococcus neoformans". NNF grant number NNF21OC0070070.
The project will run from the 1 April 2022 - 31 March 2026.
Contact: Katja Salomon Johansen
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|Anne Blicher||Laboratory Technician||+4535328028|
|Helle Jakobe Martens||Associate Professor||+4528960218|
|Jonas Thomsen||Research Assistant|
|Magnus Hallas-Møller||Assistant Professor||+4535332313|
|Signe Lett||Assistant Professor||+4535326162|
|Søren Brander||Assistant Professor||+4535331261|
|Søren Michael Nielsen||Laboratory Technician||+4535336197|
|Tania Fredborg Nielsen||Special Consultant||+4535331280|