Biopolymers and redox enzymes 

Our research is focused on the enzymes that catalyse degradation of plant cell walls in nature as well as in industrial biorefineries.

The aim is to both understand the molecular mechanisms and the systems in which the enzymes work. Our laboratories are equipped with specialised instruments that allow for study the role of oxygen in the degradation processes.

 

Special attention is given to enzymes called lytic polysaccharide monooxygenases (LPMOs). These enzyme are mononuclear copper enzymes that use oxygen-species for catalysis.

LPMOs are likely to have several functions in biology and are important for saprotrophic fungal lifestyle. Importantly, they initiate degradation of cellulose by cleaving glycosidic bonds at places that are not accessible cellulose hydrolases.

 

Ongoing Projects

Crypto
NNF Synergy grant "Mechanisms of lytic polysaccharide monooxygenases in fungal pathogenesis: directing polysaccharide structure and metabolism in Cryptococcus neoformans". NNF grant number NNF21OC0070070.
The project will run from the 1 April 2022 - 31 March 2026. 
Contact: Søren Brander

OxyMiST
Oxygen Constraints on Microbial Secretomes during Plant Cell Wall Turnover
Contact: Søren Brander

Completed Projects

HOPE
Harnessing the Oxidative Power of Enzymes
Contact: Søren Brander

 

Researchers

Name Title Phone E-mail
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Anne Blicher Laboratory Technician +4535328028 E-mail
Helle Jakobe Martens Associate Professor +4528960218 E-mail
Jonas Thomsen Research Assistant   E-mail
Magnus Hallas-Møller Assistant Professor +4535332313 E-mail
Radina Tokin Postdoc +4535326455 E-mail
Rikke Lauge Borchmann Research Assistant   E-mail
Sascha Hellmann Hansen Academic Research Officer +4535334960 E-mail
Signe Lett Assistant Professor +4535326162 E-mail
Søren Brander Assistant Professor +4535331261 E-mail

Head of Research Group


Søren Brander
Assistant Professor

sbd@ign.ku.dk
35 33 12 61