The Mothers, Infants, and Lactation Quality (MILQ) Study: A multi-center collaboration
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Dokumenter
- Allen et al_Current Development in Nutrition_2021_Vol 5(10)_nzab116
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Little valid information is available on human milk nutrient concentrations, especially for micronutrients (MNs), and there are no valid reference values (RVs) across lactation. In this multi-center collaborative study, RVs will be established for human milk nutrients across the first 8.5 mo postpartum. Well-nourished, unsupplemented women in Bangladesh, Brazil, Denmark, and The Gambia (n = 250/site) were recruited during the third trimester of pregnancy. Milk, blood, saliva, urine, and stool samples from mothers and their infants are collected identically at 3 visits (1-3.49, 3.5-5.99, 6.0-8.49 mo postpartum). Milk analyses include macronutrients, selected vitamins, trace elements and minerals, iodine, metabolomics, amino acids, human milk oligosaccharides, and bioactive peptides. We measure milk volume; maternal and infant diets, anthropometry, and morbidity; infant development, maternal genome, and the infant and maternal microbiome. RVs will be constructed based on methods for the WHO Child Growth Standards and the Intergrowth-21st Project.
This trial was registered at clinical trials.gov as NCT03254329.
Originalsprog | Engelsk |
---|---|
Artikelnummer | nzab116 |
Tidsskrift | Current Developments in Nutrition |
Vol/bind | 5 |
Udgave nummer | 10 |
Antal sider | 14 |
DOI | |
Status | Udgivet - 2021 |
Bibliografisk note
CURIS 2021 NEXS 326
© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
- Det Natur- og Biovidenskabelige Fakultet
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